On Friday, Shares of Aurinia Pharmaceuticals Inc (NASDAQ:AUPH), subtract -7.84% and closed at $4.70 in the last trading session. The last trading range of the stock ranges between $4.24 and $5.05. The company’s Market capitalization is $165.85million with the total Outstanding Shares of 35.29 million. During the 52-week trading session the minimum price at which share price traded, registered at $1.42 and reached to max level of $5.69. Aurinia Pharmaceuticals Inc. (NASDAQ:AUPH / TSX:AUP) (“Aurinia” or the “Company”) a clinical stage biopharmaceutical company focused on the global immunology market, recently declared 24-week data in all 10 patients from the AURION study, an open-label exploratory study to assess the short-term predictors of response using voclosporin (23.7mg BID) in combination with mycophenolate mofetil (MMF) and oral corticosteroids in patients with active lupus nephritis (LN). The data are being presented by Robert Huizinga, Vice President of Clinical Affairs at Aurinia at the 10th Annual European Lupus Meeting in Venice, Italy.
The primary objective of the study is to examine biomarkers of disease activity at eight weeks and their ability to predict response at 24 and 48 weeks.
In this study, 70% (7/10) patients achieved complete remission (CR) at 24 weeks as measured by a urinary protein creatinine ratio (UPCR) of ≤ 0.5mg/mg, eGFR within 20% of baseline and concomitant steroid dose of <5mg/day. Of the 10 patients that achieved a reduction of UPCR of ≥ 25% at 8 weeks, 80% were responders (≥ 50% reduction in UPCR over baseline) at 24 weeks and 70% were in CR at 24 weeks. In addition, inflammatory markers such as C3, C4 and anti-dsDNA all continued to normalize to 24 weeks. Voclosporin was well-tolerated with no unexpected safety signals observed.
General Motors Company(NYSE:GM), dropped -0.58% and closed at $32.34 in the last trading session. The last trading range of the stock ranges between $32.05 and $32.60. The company’s Market capitalization is $50.22 Billion with the total Outstanding Shares of 1.56 Billion. During the 52-week trading session the minimum price at which share price traded, registered at $26.69 and reached to max level of $36.88. General Motors Company designs, builds, and sells cars, crossovers, trucks, and automobile parts worldwide. The company operates through GM North America, GM Europe, GM International Operations, GM South America, and GM Financial segments. It markets its vehicles mainly under the Buick, Cadillac, Chevrolet, GMC, Opel, Holden, Vauxhall, Baojun, Jiefang, and Wuling brand names. The company also sells cars and trucks to dealers for consumer retail sales, in addition to to fleet customers, counting daily rental car companies, commercial fleet customers, leasing companies, and governments. In addition, it offers connected safety, security and mobility solutions, and information technology services. The company, through its partner, General Motors Financial Company, Inc., provides automotive financing services.
On the other hand share Huntington Bancshares Incorporated(NASDAQ:HBAN), gained 0.10% and closed at $10.17 in the last trading session. The last trading range of the stock ranges between $10.03 and $10.25. The company’s Market capitalization is $8.14 Billion with the total Outstanding Shares of 799.15 million. During the 52-week trading session the minimum price at which share price traded, registered at $7.83 and reached to max level of $11.87. Huntington Bancshares Incorporated operates as a holding company for The Huntington National Bank that provides commercial, small business, consumer, and mortgage banking services. The companys Retail and Business Banking segment offers financial products and services, counting checking accounts, savings accounts, money market accounts, certificates of deposit, consumer loans, and small business loans; and investments, insurance, interest rate risk protection, and foreign exchange and treasury administration services. Its Commercial Banking segment provides corporate risk administration and institutional sales, trading, and underwriting services; commercial property and casualty, employee benefits, personal lines, life and disability, and specialty lines of insurance; and brokerage and agency services for residential and commercial title insurance, in addition to excess and surplus product lines of insurance. The companys Automobile Finance and Commercial Real Estate segment offers financing for the purchase of vehicles; financing the acquisition of new and used vehicle inventory of franchised automotive dealerships; and financing for land, buildings, and other commercial real estate owned or constructed by real estate developers, automobile dealerships, or other customers. Its Regional Banking and The Huntington Private Client Group segment provides deposits, lending, and other banking services; wealth administration services, and retirement plan and corporate trust services; and brokerage, annuities, advisory, and other investment products.